PhysiologybioRxivPreprint
Beyond Kaftrio: mechanistic insights to maximize N1303K-CFTR rescue
Iwona Maria Pranke, Valeria Capurro, B. Chevalier…·Nicoletta Pedemonte
This study investigates the mechanism of N1303K-CFTR rescue by ELX/TEZ and ETI combotherapy, showing increased protein amounts and activity with potential clinical benefits.
2 citations