Impaired Cu-Zn superoxide dismutase (SOD1) and calcineurin (Cn) interaction in ALS: A presumed consequence for TDP-43 and zinc aggregation in Tg SOD1G93A rodent spinal cord tissue.
Jolene M. Kim, Elizabeth Billington, Ada Reyes, Tara Notarianni, Jessica M. Sage, Emre Agbas, Michael Taylor, Ian Monast, John A. Stanford, Abdulbaki Aǵbaş
The paper investigates impaired Cn-SOD1 interaction in ALS models, linking it to TDP-43 hyperphosphorylation and zinc aggregation.
Neurochemical Research · Jan 3, 2018Peer-reviewedNeuroscience