Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast
Oona Paavolainen, Markus Peurla, Leena M. Koskinen, Jonna Pohjankukka, Kamyab Saberi, Ella Tammelin, Suvi-Riitta Sulander, Masi Valkonen, Larissa Mourão, Pia Boström, Nina M. Brück, Pekka Ruusuvuori, Colinda L. G. J. Scheele, Pauliina Hartiala, Emilia Peuhu
This study uses 3D imaging to analyze the structure and cell phenotypes of terminal ductal lobular units (TDLUs) in human breast tissue, revealing consistent branching patterns and new organizational features.
Cell Reports · Oct 1, 2024Peer-reviewedDevelopmental Biology