Pekka Ruusuvuori

Hypoxia and Associated Acidosis Generate Cell-Type Specific Myeloid Responses in Glioblastoma

The paper investigates how hypoxia and acidosis influence myeloid cell responses in glioblastoma, revealing distinct metabolic adaptations in macrophages versus microglia.

Immune interaction signatures in adipose tissue fibroblasts in obesity-associated atherosclerosis

The paper identifies immune-related transcriptional changes in adipose-derived fibroblasts in obesity-associated atherosclerosis using single-cell RNA sequencing and spatial transcriptomics.

Volumetric analysis of the terminal ductal lobular unit architecture and cell phenotypes in the human breast

This study uses 3D imaging to analyze the structure and cell phenotypes of terminal ductal lobular units (TDLUs) in human breast tissue, revealing consistent branching patterns and new organizational features.