Dopamine Agonists in Parkinson's Disease Decouple Risk-Taking from Reward-Paired Cues by Enhancing Risky Choice in Their Absence
Katherine Muksuris, Ellen Flynn, Tanya L. Feng, Pratibha Surathi, Shanna C. Yeung, Leili Mortazavi, Anna Isberg, Martin J. McKeown, Silke Appel‐Cresswell, Catharine A. Winstanley, A. Jon Stoessl, Jason J.S. Barton, Mariya V. Cherkasova
This study shows that dopamine agonists combined with levodopa increase risky choices in Parkinson's patients even without reward-paired cues.
bioRxiv · Sep 12, 2026 · PreprintNeuroscience