Inotropic effects of 3-hydroxybutyrate in a rodent heart: pressure-volume and isolated rat ventricular trabeculae analysis
J Kropacek, Thu Thao Nguyen, Ema Hajkova, Matej Molnar, Luca Monzo, Matúš Miklovič, Vojtěch Melenovský
This study investigates the inotropic effects of 3-hydroxybutyrate in rat hearts using pressure-volume analysis and isolated ventricular trabeculae, finding direct myocardial improvement independent of beta-adrenergic signaling.
bioRxiv · Sep 21, 2026 · PreprintPhysiology