UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors
Avery J. Benton, Mia R. Johns, Emil Diamant, Nirvan Rouzbeh, Valdemar P. Sørensen, Carly M. Anderson, Davide Secci, Zhucheng Zhang, Andrew R. Rau, Rasmus P. Clausen, Kasper Bø Hansen
This paper introduces UCM-A86, a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors, showing specific potentiation without affecting GluN2-containing receptors or AMPA receptors.
Molecular Pharmacology · Jan 24, 2026Peer-reviewedNeuroscience