Do we really understand the role of the prefrontal cortex in placebo analgesia?
Eleni Frangos, Nicholas Madian, Binquan Wang, Megan L Bradson, John L. Gracely, Emily A. Richards, Luana Colloca, Petra Schweinhardt, Mary Catherine Bushnell, Marta Čeko
This study investigates the role of the prefrontal cortex in placebo analgesia by comparing brain activity during high and low heat conditions with inert creams, finding reduced prefrontal activation despite lower pain ratings.
bioRxiv · Jun 18, 2021 · PreprintNeuroscience