A comprehensive pharmacodynamic dataset reconciles 50 years of laboratory and clinical knowledge
Eugene F. Douglass, Chinmay Joshi, Emily Hannan, Tobin Paez, Elizabeth A. Hughes, Jonathan Paul Mochel
This paper creates a large clinical dataset linking drug efficacy metrics to cancer outcomes and shows that exposure normalization improves the alignment between lab and clinical results.
bioRxiv · Sep 22, 2025 · PreprintPharmacology & Toxicology