Loss of dystrophin reduces CB1 receptor expression and endocannabinoid-dependent synaptic plasticity in the cerebellar cortex
Emily T Averyt, Shaarang Mitra, Jason R. Pugh
This study shows that dystrophin loss in DMDmdx mice reduces CB1 receptor expression and endocannabinoid-dependent synaptic plasticity in the cerebellum, suggesting potential therapeutic targets for CNS symptoms in DMD.
bioRxiv · Mar 20, 2026 · PreprintNeuroscience