A Single-Cell and Spatial 3D Multi-omic Atlas of Developing Human Basal Ganglia and Inhibitory Neurons
Matthew G. Heffel, Heng Xu, Oier Pastor-Alonso, Xinzhe Li, Mohammad S. Baig, Rayyan Irfan Ghoor, Runjia Li, Colin Kern, Joonho Kum, Yi Zhang, Jon Paino, Min Jen Tsai, Chu-Yi Tai, Grant Tucker, Zoey Zhao, , Chongyuan Luo
This study creates a 3D multi-omic atlas of developing human basal ganglia and inhibitory neurons, revealing lineage-specific 3D genomic dynamics and regulatory programs associated with neuropsychiatric disease risk.
bioRxiv · Jan 29, 2026 · PreprintGenomics