Prediction of TdP Arrhythmia Risk Through Molecular Simulations of Conformation-specific Drug Interactions with the hERG K+, NaV1.5, and CaV1.2 Channels
Kyle C. Rouen, Kush Narang, Yanxiao Han, David Wang, Ensley Jang, Sophia Brunkow, Vladimir M. Yarov-Yarovoy, Alexander D. MacKerell, Igor V. Vorobyov
bioRxiv · Sep 25, 2025 · PreprintBiophysics