Establishment of an in vitro culture system to study the developmental biology (growth, mating and nodule formation) of Onchocerca volvulus with implications for anti-onchocerca drug discovery and screening
Narcisse Victor Tchamatchoua Gandjui, Abdel Jélil Njouendou, Eric Njih Gemeg, Fanny Fri Fombad, Manuel Ritter, Chi Anizette Kien, Valerine Chawa Chunda, Jerome Fru, Mathias Eyong Esum, Marc Peter Hübner, Peter Enyong, Achim M. Hoerauf, Samuel Wanji
This paper establishes an in vitro culture system to maintain and develop Onchocerca volvulus larvae to adult stages, enabling study of mating, nodule formation, and drug screening.
PLoS neglected tropical diseases · Feb 9, 2021Peer-reviewedDevelopmental Biology