Single-cell RNA-sequencing of cerebral spinal fluid identifies circulating tumour cells in children with brain cancer
Chelsea Mayoh, Wenyan Li, Mojgan Toumari, Sajad Razavi Bazaz, Anne‐Lise Gérard, Aileen Lowe, Paulette Barahona, Loretta MS Lau, Jordan Staunton, Erica E. Jacobson, Sumanth Nagabushan, Neevika Manoharan, Ruth A. Mitchell, Faustine Ong, Marie Wong, , Robert Salomon
This study uses single-cell RNA-sequencing of cerebrospinal fluid to identify circulating tumour cells in children with brain cancer, revealing their dynamics and potential as biomarkers.
bioRxiv · Dec 22, 2025 · PreprintCancer Biology