Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons
Jason P. Chua, Karan Bedi, Michelle T. Paulsen, Mats E. Ljungman, Elizabeth M.H. Tank, Erin S. Kim, Jonathon P. McBride, J Colon, Michael Emmerson Ward, Lois S. Weisman, Sami J. Barmada
This study identifies MTMR5 as a neuron-specific autophagy suppressor, showing its role in limiting autophagy and its potential as a therapeutic target for neurodegenerative diseases.
Current Biology · May 16, 2022Peer-reviewedNeuroscience