Exome sequencing in Asian populations identifies rare deficient SMPD1 alleles that increase risk of Parkinson's disease
Elaine Guo Yan Chew, Zhehao Liu, Zheng Li, Sun Ju Chung, Michelle Mulan Lian, Moses Tandiono, Ebonne Ng, Louis Tan, Wee Ling Chng, Tiak Ju Tan, Esther KL Peh, Ying Swan Ho, Xiao Yin Chen, Erin YT Lim, Chu Hua Chang, , Jia Nee Foo
The paper identifies rare SMPD1 variants in Asian populations that increase Parkinson's disease risk through exome sequencing and functional assays.
medRxiv · Aug 3, 2023 · PreprintGenetic & Genomic Medicine