Jia Nee Foo

The paper identifies the LRRK2 p.A419V variant as a significant risk factor for Parkinson's disease in East Asian populations and explores its association with age of onset.

This study compares polygenic risk scores for Parkinson's disease across seven ancestries, finding varying predictive accuracy and highlighting the need for ancestry-specific models.

The paper shows ancestry-specific gene expression in monocytes mediates neurodegenerative disease risk through innate immune cell expression of neurodegeneration-related genes.

The paper identifies rare SMPD1 variants in Asian populations that increase Parkinson's disease risk through exome sequencing and functional assays.

The paper investigates RIC3 variants' association with Parkinson's Disease in multiple cohorts and finds no significant association.

This study examines how parental bonding and the oxytocin receptor gene polymorphism (rs53576) interact to influence anxiety and avoidance in adult relationships among young adults in Italy and Singapore.

This study finds a gene-environment interaction where oxytocin receptor genotype and nanny experience influence face categorization reaction times in adults.

The paper presents a GWAS locus browser for Parkinson's disease that helps prioritize genes associated with risk variants from multiple GWAS studies.

The paper shows that trisomy 21 cerebral organoids exhibit AD-like pathology, which can be suppressed by BACE2 trisomy and inhibited by BACE1 inhibitors, suggesting BACE2 as an AD-suppressor gene.

This study presents whole-genome sequencing data from 4,810 Singaporeans across three ethnic groups, revealing genetic structure, admixture, and improved imputation for Asian and Oceanian populations.

This paper develops a cost-effective and efficient sequencing protocol for the filaggrin gene to detect disease-associated variants across diverse populations.