Molecular BiologybioRxivPreprint
Rac1 deficiency reduces mitochondrial respiratory capacity, impairs fatty acid metabolism and causes muscle wasting
Lisbeth L. V. Møller, Steffen Henning Raun, Emma Frank…·Lykke Sylow
This study shows that Rac1 deficiency in muscle reduces mitochondrial function and fatty acid metabolism, leading to muscle wasting and highlights potential therapeutic targets for age-related muscle decline.