Anders Karlsen

Rac1 deficiency reduces mitochondrial respiratory capacity, impairs fatty acid metabolism and causes muscle wasting

This study shows that Rac1 deficiency in muscle reduces mitochondrial function and fatty acid metabolism, leading to muscle wasting and highlights potential therapeutic targets for age-related muscle decline.

Distinct myofibre domains of the human myotendinous junction revealed by single nucleus RNA-seq

The paper uses single nucleus RNA-seq to identify distinct myonuclei profiles at the human myotendinous junction, revealing gene expression patterns and subclusters associated with specific proteins and fibre types.