Joint models reveal genetic architecture of transitions between pubertal stages and their association with BMI in a Latino population
Lucas Vicuña, Esteban Barrientos, Valeria Leiva-Yamaguchi, Danilo Alvares, Verónica Mericq G, Ana Paula Rodrigues Pereira, S. Eyheramendy
The paper identifies genetic variants associated with pubertal stage transitions and BMI using joint models in a Latino cohort, finding 43 novel associations and links between Native American ancestry and earlier Tanner 2 stage onset in boys.
medRxiv · Jun 29, 2023 · PreprintGenetic & Genomic Medicine