ANALYSIS OF CHD-7 DEFECTIVE DAUER NEMATODES IMPLICATES COLLAGEN MISREGULATION IN CHARGE SYNDROME FEATURES.
Diego M. Jofré, Dane K. Hoffman, Ailen Soledad Cervino, Gabriella M. Hahn, McKenzie K. Grundy, Sijung Yun, Francis R. G. Amrit, Donna Beer Stolz, Luciana F. Godoy, Esteban Salvatore, Fabiana Alejandra Rossi, Arjumand Ghazi, M. Cecilia Cirio, Judith L. Yanowitz, Daniel Hochbaum
This paper identifies chd-7's role in collagen regulation in nematodes and vertebrates, linking it to CHARGE syndrome features through extracellular matrix misregulation.
Proceedings of the National Academy of Sciences · Apr 8, 2022Peer-reviewedGenetics