Preictal high-connectivity states in epilepsy: Evidence of intracranial EEG, interplay with the seizure onset zone and network modeling
Nicolas Medina, Manel Vila‐Vidal, Ana Tost, Mariam Khawaja, Mar Carreño, Pedro Roldán, Jordi Rumià, María Centeno, Estefanía Conde, Antonio Donaire, Adrià Tauste Campo
The paper identifies high-connectivity states (HCS) as a pre-seizure biomarker in epilepsy, showing increased probability hours before seizures and linking it to seizure-onset zone dynamics.
Journal of Neural Engineering · Jul 16, 2025Peer-reviewedNeuroscience