The ANKS3/BICC1 protein complex is a master post-transcriptional regulator of NPHP1 ciliopathy gene transcripts
Alexia Mahuzier, Gweltas Odye, Valentina Grampa, Albane Bizet, Amandine Viau, Rebecca Ryan, Manon Mehraz, Thierry Blisnick, Euan Clark, Charline Henry, Rémi Piedagnel, Flora Silbermann, Gaelle Hayot, Line De grande, Agathe Kahn, , Sophie Saunier
The paper identifies ANKS3/BICC1 as a post-transcriptional regulator of NPHP1 transcripts, linking it to ciliopathy phenotypes through transcript decay and ciliary dysfunction.
bioRxiv · Apr 18, 2024 · PreprintPathology