Protein UFMylation regulates early events of ribosomal DNA double-stranded break response
Pudchalaluck Panichnantakul, Lisbeth C. Aguilar, Evan Daynard, Mackenzie Guest, Colten Peters, Jackie Vogel, Marlene Oeffinger
This study identifies UFMylation as essential for rDNA DSB response, showing UFL1 and DDRGK1 localize to nucleolar caps and regulate ATM activation and rDNA silencing.
bioRxiv · Feb 14, 2024 · PreprintMolecular Biology