Carbon-negative biosynthesis of pyrone and pyridine dicarboxylic acids from terephthalic acid via continuous mixotrophic gas fermentation in Cupriavidus necator H16
Ewan W. Waters, Alex v.E. Conradie, Rajesh Reddy Bommareddy
This paper describes a carbon-negative bioprocess using Cupriavidus necator H16 to convert terephthalic acid into value-added chemicals, achieving complete conversion to 2-pyrone-4,6-dicarboxylic acid.
bioRxiv · Mar 16, 2026 · PreprintBioengineering