Isavuconazole therapeutic drug monitoring associated to a pharmacogenetic exploration is far from being a pharmacologists’ whim
L Darnaud, F Lamoureux, C Godet, S Pontier, A Debard, N Venisse, P Martins, D Concordet, P Gandia
The paper reports four cases of isavuconazole toxicity and suggests pharmacogenetic testing to guide dosing based on CYP3A4/5 polymorphisms.
bioRxiv · May 9, 2018 · PreprintPharmacology & Toxicology