Continuous B- to A- Transition in Protein-DNA Binding - How Well Is It Described by Current AMBER Force Fields?
P. Jurecka, M. Zgarbova, F. Cerny, J. Salomon
This study evaluates how current AMBER force fields model the A/B DNA transition in protein-DNA complexes, finding underestimation of A-like intermediate states' stability.
bioRxiv · Jan 13, 2022 · PreprintBiophysics