DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity
S. Sauvaigo, M. Benkhiat, F. Braisaz, S. Libert, J. Girard, S. Mouret, F. de Fraipont, C. Aspord, F. Bouquet, M.-T. Leccia
This study classifies melanoma cell lines based on DNA repair capacity, showing that BRAF and NRAS mutations affect BER and NER, and that targeted therapy alters repair activity.
bioRxiv · Apr 29, 2020 · PreprintCancer Biology