Structures of ferroportin in complex with its specific inhibitor vamifeport
E. F. Lehmann, M. Liziczai, K. Drozdzyk, P. Altermatt, V. Manolova, H. Sundstrom, F. Duerrenberger, R. Dutzler, C. Manatschal
This study presents cryo-EM structures of ferroportin bound to vamifeport and nanobodies, revealing conformational changes and the inhibitor's binding site.
bioRxiv · Aug 29, 2022Biochemistry