Neuroprotective tissue adaptation induced by IL-12 attenuates CNS inflammation
M. Andreadou, F. Ingelfinger, D. De Feo, E. Friebel, S. Tuzlak, T. M. L. Cramer, B. Schreiner, P. Eede, S. Schneeberger, M. Geesdorf, F. Ridder, C. A. Welsh, D. Kirschenbaum, S. K. Tyagarajan, M. Greter, , B. Becher
The paper identifies IL-12-responsive neuroectoderm cells that mediate neuroprotection in CNS inflammation, with parallels observed in human MS.
bioRxiv · Sep 14, 2022 · PreprintImmunology