F. L. Barroso da Silva

Electrostatic features for the Receptor binding domain of SARS-COV-2 wildtype and its variants. Compass to the severity of the future variants with the charge rule.

The paper analyzes electrostatic features of SARS-CoV-2 RBD variants to predict binding affinity and severity using a charge-based rule.

Differences between Omicron SARS-CoV-2 RBD and other variants in their ability to interact with cell receptors and monoclonal antibodies

This paper uses simulations to compare Omicron and other SARS-CoV-2 variants' RBD interactions with ACE2 and mAbs, identifying binding affinities and potential therapeutic targets.

Towards an optimal monoclonal antibody with higher binding affinity to the receptor-binding domain of SARS-CoV-2 spike proteins from different variants

The paper uses a multiscale computational protocol to design mAbs with higher binding affinity to SARS-CoV-2 spike protein RBD across variants, identifying candidates with improved performance against Omicron.

On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2

This study maps electrostatic epitopes and interaction energies of SARS-CoV-1 and SARS-CoV-2 RBD proteins with antibodies and ACE2, showing higher ACE2 binding affinity for SARS-CoV-2 RBD.

Repositioning septins within the core particle

This study characterizes the structure of a septin hexamer, revealing an inverted arrangement compared to previously reported models and showing compatibility with yeast structures.