Cell BiologyScientific ReportsPeer-reviewed
A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data
F. Mazet, M. Tindall, J. Gibbins, M. Fry
The paper develops a computational model of the PI cycle using single-cell proteomic data from platelets, showing that mosaic data from multiple cell types lead to inconsistent predictions.
DOI 10.1038/s41598-020-70215-7