Computational Analysis of Dynamical Fluctuations of Oncoprotein E7 (HPV) for the Hot Spot Residue Identification Using Elastic Network Model
Rabbiah Manzoor Malik, F. Nazir, S. Fazal, A. Bhatti, M. Ullah, S. I. Malik, A. Kanwal, S. E. Aziz, S. Azam
The paper uses an elastic network model to analyze dynamic fluctuations of HPV E7 protein and identifies hot spot residues in the LxCxE motif critical for its interaction with Rb, contributing to cervical cancer progression.
Letters in Drug Design & Discovery · Jun 6, 2020Peer-reviewedBioinformatics