Cell type-specific assessment of cholesterol distribution in models of neurodevelopmental disorders
C. Czernecki, S. Dixit, I. Riezman, S. Innocenti, F. Pfrieger, H. Riezman, P. Scheiffele
The paper develops genetically-encoded sensors to assess cell type-specific cholesterol distribution in mouse models of neurodevelopmental disorders and identifies distinct cholesterol homeostasis phenotypes in Npc1 and Ptchd1 knock-out mice.
bioRxiv · Nov 16, 2022 · PreprintNeuroscience