Chromatin sensing by the auxiliary domains of KDM5C regulates its demethylase activity and is disrupted by X-linked intellectual disability mutations
F. S. Ugur, M. J. S. Kelly, D. Galonic Fujimori
This study investigates how accessory domains of KDM5C regulate its demethylase activity and how XLID mutations disrupt this regulation.
bioRxiv · Jan 13, 2022Biochemistry