Glucose controls co-translation of structurally related mRNAs via the mTOR and eIF2 pathways in human pancreatic beta cells
Manuel Bulfoni, Costas Bouyioukos, Albatoul Zakaria, Fabienne Nigon, Roberta Rapone, Laurence Del Maestro, Slimane Ait‐Si‐Ali, Raphaël Scharfmann, Bertrand Cosson
This study shows glucose induces translational regulation of over 400 mRNAs in human pancreatic beta cells via mTOR and eIF2 pathways, independent of transcriptional changes.
Frontiers in Endocrinology · Aug 5, 2022Peer-reviewedGenomics