A small increase in CHEK1 activity leads to the arrest of the first zygotic division in human
Beili Chen, Jianying Guo, Ting Wang, Qianhui Lee, Jia Ming, Fangfang Ding, Haitao Li, Zhiguo Zhang, Lin Li, Yunxia Cao, Jie Na
The paper shows that a small increase in CHEK1 activity causes arrest of the first zygotic division in human embryos, with implications for assisted reproduction.
bioRxiv · Dec 26, 2020 · PreprintDevelopmental Biology