Non-native Interactions Explain the Folding Rate Differences in α-Spectrin Domains and the Origin of Internal Friction Effects
Fernando Bruno da Silva, Vinícius G. Contessoto, Vinícius M. de Oliveira, Jane Clarke, Vitor B. P. Leite
The paper investigates internal friction in protein folding by simulating α-spectrin domains with non-native interactions, showing that cooperativity among these interactions explains folding rate differences and internal friction effects.
bioRxiv · Dec 10, 2017 · PreprintBiophysics