Author

Fernando Bruno da Silva

University of WarsawORCID 0000-0002-0285-8700Unclaimed ORCID profile · follow to get notified of new preprints

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Fernando Bruno da Silva1 paper

Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

Joanna Ida SulkowskaiD· 2 shared Agata P. PerlinskaiD· 1 shared Erica FlapaniD· 1 shared Iwona LewandowskaiD· 1 shared Jacek PłonkaiD· 1 shared Katarzyna M. TychiD· 1 shared Laura‐Marie SilbermanniD· 1 shared Maciej SikoraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Joanna Ida SulkowskaORCID

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2 papers

Recent·Most cited

Multi-barrier unfolding of the double-knotted protein, TrmD-Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

Fernando Bruno da Silva, Szymon Niewieczerzał, Iwona Lewandowska, Mateusz Fortunka, Maciej Sikora, Laura‐Marie Silbermann, Katarzyna M. Tych, Joanna Ida Sulkowska

This study uses single-molecule force spectroscopy and molecular dynamics to analyze the unfolding and folding of double-knotted and single-knotted proteins, revealing that double-knotted proteins require chaperone assistance for full knotting.

bioRxiv · Aug 27, 2025 · PreprintBiophysics

Universe of Lasso Proteins: Exploring the limit of entanglement and folding landscape of proteins predicted by AlphaFold

Fernando Bruno da Silva, Agata P. Perlinska, Jacek Płonka, Erica Flapan, Joanna Ida Sulkowska

The paper uses AlphaFold to analyze protein structures and identifies new lasso motifs, including knotted lasso proteins, and explores their topological complexity and conservation.

bioRxiv · Mar 21, 2025 · PreprintBiophysics