LTA4H association with montelukast response in early and late-onset asthma
Cyrielle Maroteau, Antonio Espuela‐Ortiz, Esther Herrera Luis, Sundararajan Srinivasan, Fiona Carr, Roger Tavendale, Karen Wilson, Natalia Hernandez‐Pacheco, James Duncan Chalmers, Steve Turner, Somnath Mukhopadhyay, Anke H. Maitland‐van der Zee, Esteban G. Burchard, Maria del Mar Pino-Yanes, Simon S Young, , Colin N. A. Palmer
This study investigates the association between LTA4H genetic variant rs2660845 and montelukast response in early-onset asthma, finding increased exacerbation risk in European carriers.
PLoS ONE · Sep 22, 2021Peer-reviewedGenetic & Genomic Medicine