Real-time mass-resolved label-free single-molecule immunoassay
Carraugh C. Brouwer, Flaminia M. Muratori, Luke Melo, Luigi Anastasia, Carlo Pappone, Edward R. Grant
This paper introduces a label-free, real-time single-molecule immunoassay using iSCAT to directly observe protein-protein interactions with high sensitivity and molecular-weight resolution.
bioRxiv · Feb 18, 2026 · PreprintBiophysics