Author

Luigi Anastasia

Vita-Salute San Raffaele UniversityORCID 0000-0002-0712-2161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Carlo PapponeiD· 2 shared Alice NevoneiD· 1 shared Anthony FrosioiD· 1 shared Carraugh C. BrouweriD· 1 shared Dario MelgariiD· 1 shared Davide Pignatelli· 1 shared Edward R. GrantiD· 1 shared Federica Sonzini· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPathology

Carlo PapponeORCID

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2 papers

Recent·Most cited

Exploring light chain cardiotoxicity in AL amyloidosis: Impact on hiPSC-derived Cardiomyocyte Activity

Serena Calamaio, Anthony Frosio, Dario Melgari, Luca Broggini, Federica Sonzini, Rachele Prevostini, Davide Pignatelli, Luigi Anastasia, Carlo Pappone, Alice Nevone, Giovanni O. Palladini, Mario Nuvolone, Stéfano Ricagno, Ilaria Rivolta

This study uses hiPSC-derived cardiomyocytes to show that cardiotoxic light chains reduce electrophysiological function, while non-toxic light chains have no effect.

Amyloid · Jun 19, 2026Peer-reviewedPathology

Real-time mass-resolved label-free single-molecule immunoassay

Carraugh C. Brouwer, Flaminia M. Muratori, Luke Melo, Luigi Anastasia, Carlo Pappone, Edward R. Grant

This paper introduces a label-free, real-time single-molecule immunoassay using iSCAT to directly observe protein-protein interactions with high sensitivity and molecular-weight resolution.

bioRxiv · Feb 18, 2026 · PreprintBiophysics