Genetically flexible but conserved: a new essential motif in the C-ter domain of HIV-1 group M integrases
Marine Kanja, Pierre Cappy, Nicolas Levy, Oyindamola Oladosu, Sylvie Schmidt, Paola Rossolillo, Flore Winter, Romain Gasser, Christiane Moog, Marc Ruff, Matteo Negroni, Daniela Lener
The paper identifies a conserved but genetically flexible motif in HIV-1 integrase's C-terminal domain that is essential for integration and other functions.
bioRxiv · May 26, 2020 · PreprintMolecular Biology