Towards reconstruction of the human interactome from positive and negative experimental evidence
Joel Ås, K. Pelz, Judith Bernett, Francesco Battini, Markus List, David B. Blumenthal, Martin H. Schaefer
Inferring tested-but-undetected pairs from prey lists of 5,530 published interaction screens yields 97 million tested human protein pairs and 18,982,508 non-interactions (≥3 tests) for calibrating screens and predictors.
bioRxiv · Sep 13, 2026 · PreprintBioinformatics✦ In-depth digest