Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells
Denis J. Ohlstrom, Mojtaba Bakhtiari, Hope Mumme, Marina E. Michaud, Alejandro de Janon, Deborah DeRyckere, Katherine E. Ferguson, Frank Chien, William Pilcher, Sarthak Satpathy, Sean C. Jordan, Douglas K. Graham, Swati Sharma Bhasin, Manoj Bhasin
This study uses single-cell RNA sequencing to identify treatment-resistant subtypes and mast cell-like cells in pediatric AML, linking them to poor outcomes.
Leukemia · Sep 10, 2025Peer-reviewedCancer Biology