Massively multiplex single-cell Hi-C
Vijay Ramani, Xinxian Deng, Kevin L Gunderson, Frank J Steemers, Christine M Disteche, William S Noble, Zhijun Duan, Jay Shendure
This paper introduces combinatorial single cell Hi-C, a method for measuring chromosome conformation in single cells, and shows its ability to distinguish cell types and reveal chromosomal heterogeneity.
Nature Methods · Jan 30, 2017Peer-reviewedGenomics