Reactivity-based screening for citrulline-containing natural products reveals a family of bacterial peptidyl arginine deiminases
L. A. Harris, P. M. B. Saint-Vincent, X. Guo, G. A. Hudson, D. A. Mitchell
The paper identifies a family of bacterial peptidyl arginine deiminases (PADs) responsible for arginine deimination in lasso peptides, leading to citrulline-containing variants.
bioRxiv · Jul 16, 2020Biochemistry