G. A. Lobinska

Phenotype switching of the mutation rate facilitates adaptive evolution

This paper shows that switching between mutator and non-mutator phenotypes enhances adaptive evolution by maintaining mutator states and increasing the likelihood of adaptive mutations.

Evolutionary safety of death by mutagenesis

The paper assesses the evolutionary safety of antiviral drugs that induce mutagenesis, finding that Molnupiravir is narrowly safe under current parameters and suggests strategies to improve safety.

Phenotype switching of the mutation rate as a strategy for crossing fitness valleys

This paper shows that intermediate mutation rate switching enhances adaptation on rugged fitness landscapes by enabling the crossing of fitness valleys and reducing deleterious mutation accumulation.