Benzylic Radical Stabilization Permits Ether Formation During Darobactin Biosynthesis
A. M. Woodard, F. Peccati, C. D. Navo, G. J. Oses, D. A. Mitchell
This paper investigates how DarE enzyme modifies DarA to form ether and C-C crosslinks, identifying key residues and mechanisms involved in radical-mediated biosynthesis.
bioRxiv · Nov 29, 2023 · PreprintBiochemistry