Gaussian curvature and the budding kinetics of enveloped viruses
M. F. Hagan, R. Bruinsma, S. Dharmavaram, S. B. She, G. Lazaro
The paper explains that the stalling of enveloped virus budding is due to a geometrical energy barrier caused by curvature conflicts between the viral capsid and the neck region, which can be overcome by the ESCRT machinery.
bioRxiv · Oct 30, 2018Biophysics